Center for Behavioral and Preventive Medicine

Laura R. Stroud, PhD

  

  Assistant Professor (Research),
  Dept. of Psychiatry & Human Behavior
  Brown Medical School


  Staff Psychologist
,
  The Miriam Hospital

 

Centers for Behavioral and Preventive Medicine
Coro Building, Suite 500
One Hoppin Street
Providence, Rhode Island 02903
Phone:  (401) 793-8194 or (401) 454-3889
Email: Laura_Stroud@Brown.edu
Fax: (815) 346-1070 or (401) 793-8059

Laura Stroud, PhD, is an assistant professor of psychiatry and human behavior at Brown Medical School and The Miriam Hospital. Her broad research interests include, physiological responses to stress, biobehavioral mechanisms in nicotine dependence and sex differences in depression. Stroud currently has two lines of research: the first focuses on the effects of maternal smoking during pregnancy on physiological (adrenocortical) responses to stress in adolescents and infants; the second focuses on sex differences in physiological responses to stress and depression over puberty. She supervises a number of undergraduate thesis projects and independent studies. Stroud currently co-teaches an undergraduate course, Stress and Disease, BC0121 at Brown.

 

  • Faculty Scholar, Tobacco Etiology Research Network of the Robert Wood Johnson Foundation, 2002
  • Career Development Award, National Institute of Mental Health
  • New Investigator Research Award from the Society for Research on Nicotine and Tobacco, 2001
  • Junior Investigator Award from the National Alliance for Research on Schizophrenia and Depression


Adrenocortical Stress Reactivity and the Emergence of Sex Differences in Depression
Laura Stroud, Ph.D. (PI)

The long-term objective of this Junior Investigator Award is to investigate mechanisms underlying the emergence of gender differences in depression during puberty/adolescence. This project examines adrenocortical responses to interpersonal and instrumental stress in pre and post-pubertal boys and girls. Results have implications for prevention and treatment of adolescent and adult depression, and for reducing greater rates of depression in females.

HPA Reactivity, Puberty, & Sex Differences in Depression
Laura Stroud, Ph.D. (PI)

The objective of this mentored patient-oriented research career development award is to obtain training in stress responses and depression in adolescents and to develop a program of research examining: a) How do HPA responses to stress change across puberty in boys and girls? and b) Do changes in HPA responses to stress over puberty influence the emergence of sex differences in depression? This work has implications for targeted intervention and prevention efforts to diminish sex differences in adolescent depression. It should also elucidate basic interactions between the gonadal and stress axes over puberty.

Maternal Depression during Pregnancy and Adrenocortical Stress Reactivity in Infants
Laura Stroud, Ph.D (PI)

Infants born to mothers who are depressed during pregnancy have shown a variety of behavioral and physiological deficits. However, despite links between stress, hypothalamic pituitary adrenocortical (HPA) functioning and depression, and preclinical research showing effects of prenatal stress on offspring HPA functioning, no studies have examined the effects of maternal depression during pregnancy on infant HPA functioning. The objective of this Junior Investigator Award is to investigate differences in adrenocortical reactivity between infants of mothers who were depressed during pregnancy compared to infants of control mothers.

Prenatal Smoking Exposure and Infant Cortisol Reactivity
Laura Stroud, Ph.D. (PI) 

The long-term objective of this study is to elucidate neurobiological mechanisms underlying the adverse effects of prenatal tobacco exposure. This study examines differences in adrenocortical reactivity in infants exposed and unexposed to maternal smoking during pregnancy. Results will clarify the distinctive effects of smoking exposure in human offspring, and should provide pilot data for a program of research examining the effects of prenatal smoking exposure on HPA stress responses. Results may also contribute to novel and targeted treatment strategies to reverse deficits from smoking exposure.


Kassel, J., Stroud, L. R., & Paronis, C. (In Press). Smoking, stress, and negative affect: Association and mechanisms across stages of smoking. Psychological Bulletin.

Law, K., Stroud, L., Lagasse, L., Bocanegra, M., Niaura, R., & Lester, B. (in press). Maternal smoking during pregnancy and newborn neurobehavior. Pediatrics.

Niaura, R. S., Todaro, J., Stroud, L.R., Ward, K. D., Spiro, A., Aldwin, C., Landsberg, L., & Weiss, S. T. (In Press). Hostility, The Metabolic Syndrome, and Incident Coronary Heart Disease. Health Psychology.

Salovey, P., Stroud, L. R., Woolery, A., & Epel, E. S. (2002). Perceived emotional intelligence, stress reactivity, and health: Further explorations using the Trait Meta-Mood Scale. Psychology and Health, 17, 611-627.

Stroud, L. R., Niaura, R. S., Stoney, C. M. (2001). Sex differences in cardiovascular reactivity to physical appearance and performance challenges. International Journal of Behavioral Medicine, 8, 240-250.

Stroud, L. R., Salovey, P., & Epel, E. (2002). Sex differences in adrenocortical responses to achievement and interpersonal stress. Biological Psychiatry, 52, 318.

Stroud, L. R., Tanofsky-Kraff, M., Wilfley, D. E., & Salovey, P. (2000). The Yale Interpersonal Stressor (YIPS): Affective, physiological, and behavioral response to a novel interpersonal rejection paradigm. Annals of Behavioral Medicine, 22, 1-11.