Large-scale registry of children and adults with autism will provide better insight into origins of autism
The Rhode Island Consortium for Autism Research
and Treatment (RI-CART), a group of the state’s leading experts on autism
research, education, health and services, is currently enrolling new
participants in its confidential statewide registry. The data collected from
the large-scale registry will help identify genes involved in autism spectrum
disorders (ASDs) and related developmental disorders to better understand the
origins of autism.
is a complex neurodevelopmental condition that emerges in childhood. Autistic
warning signs include complex symptoms that appear prior to age three, such as
abnormal communication and social interaction, and rigid and repetitive
stereotyped behaviors. Options for diagnosis and treatment of autism remain
limited – leading to the need for larger-scale studies of the origins of
autism, and how best to identify and provide effective treatment as soon as
is led by Eric Morrow MD, PhD, an assistant
professor in biology at Brown University and a genetics researcher at Bradley
Hospital, and Stephen Sheinkopf, PhD, an assistant professor of pediatrics,
psychiatry and human behavior at The Warren Alpert Medical School of Brown
University and a clinical psychologist and researcher at Women & Infants
Hospital. The RI-CART team will initially enroll 2,000 children and
adults living in Rhode Island and surrounding communities, who have been
carefully assessed clinically, into a confidential research registry.
collected from the group will help identify genes involved in autism spectrum
disorders (ASDs) and related developmental disorders. These discoveries will
help explain the medical causes of autism, improve abilities to make an early
diagnosis and potentially guide treatments. A clinical assessment will also be
conducted, and enrollment will help to support future studies. Additional
information collected about health care and services for adults with ASD will
help to understand satisfaction with, and barriers to, receiving care in this
term RI-CART projects will also benefit from the data in the registry,
including examining early diagnosis and treatment, studying the causes of ASD,
and reviewing treatments and support for people with ASD.
study is supported by a grant from the Brown
Institute for Brain Science, the Norman Prince Neurosciences Institute, the
Brown Department of Psychiatry and Human Behavior, Bradley Hospital, The Rhode
Island Foundation, and the Department of Pediatrics at Women & Infants
Hospital, along with a major grant from the Simons Foundation.
information about RI-CART, its research, or to enroll in the registry, please
call 401-432-1200, email RICART@Lifespan.org,
or visit www.AutismRI.org.