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  • Renal Artery Stenting for High Blood Pressure Study

  • Renal Artery Stenting for High Blood Pressure Study

    The department of vascular interventional radiology at Rhode Island Hospital is participating in a multi-center trial for patients with high blood pressure (hypertension), which is caused by a narrowing in the renal artery. High blood pressure is a very common disease. In approximately 5% of people with high blood pressure, narrowing of the renal artery is the identifiable cause. Signs that hypertension may be caused by renal artery stenosis include young age, no family history of high blood pressure, and high blood pressure that was well controlled but is now difficult to manage.

    Timothy Murphy, MD, is the principal investigator of this study at Rhode Island Hospital, while Cordis Corporation, Centocor Inc., and Medical College of Ohio are the sponsors.

    Are you eligible?

    You may be eligible if you:

    • Are over the age of 18 and have high blood pressure,
    • Have any one of the following: congestive heart failure, poor kidney function or angina (chest pain) or a history of any one of the above.

    About the study

    The goal of this study is to determine if renal artery stenting with or without other protection is helpful in reducing high blood pressure. If you have a narrow artery to your kidney the narrowed artery will be opened using a stent placed by an interventional radiologist. The stent is a stainless steel mesh-like tube permanently implanted to keep open the kidney artery. This stent used in this trial is FDA (Food and Drug Administration) approved for the implantation in the biliary tract (drainage system of the liver). You may also qualify for additional protection of your kidney during the procedure using a filter and medication to thin your blood.

    Angioguard is a special filter, which opens up like a tiny protective basket or umbrella allowing blood to flow through but capturing any particles that may be dislodged during the stenting procedure that potentially can damage the function of the kidney.

    Also in this study a medication Abciximab, also called Reopro, will be used that thins the blood. It prevents clotting and clumping together of the blood particles

    What's involved?

    Participants will be screened by the vascular and interventional radiologists to determine if there is a narrowing of the blood vessels supplying the kidneys. The procedure will take approximately two hours and participants wills be require to stay in the hospital overnight. Participants are also required to come back for a 1-month and a 6-month follow-up after his/her procedure. Participants will be compensated for their time. A free parking voucher will be available.

    For more information please contact Timothy Murphy, MD, at 401-444-5194.