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Lifespan’s A - Z Health Information Library |
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Megaloblastic anemiaDefinitionMegaloblastic anemia is a blood disorder in which there is anemia with larger-than-normal red blood cells. Alternative NamesAnemia - megaloblastic CausesMegaloblastic anemia is usually caused by a deficiency of folic acid or vitamin B12. Other causes are:
Risk factors relate to the causes. See also: Pernicious anemia Symptoms
Exams and TestsExamination of the nervous system may show:
TreatmentThe first goal is to diagnose the cause of the anemia. The treatment depends on the cause. Anemias related to specific vitamin deficiencies are discussed separately. Outlook (Prognosis)The outcome depends on the cause of the anemia. Possible ComplicationsComplications vary with the cause of the anemia. When to Contact a Medical ProfessionalCall for an appointment with your health care provider if you develop symptoms of this condition. PreventionGetting enough vitamin B12 and folic acid is helpful. ReferencesAntony AC. Megoblastic anemias. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 170. Review Date: 11/23/2008
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. The information provided herein should not be used during any
medical emergency or for the diagnosis or treatment of any medical
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information only -- they do not constitute endorsements of those
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