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Lifespan’s A - Z Health Information Library |
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Takayasu arteritisDefinitionTakayasu arteritis is an inflammation of the aorta -- the artery that carries blood from the heart to the rest of the body -- and its major branches. Alternative NamesPulseless disease CausesThe cause of Takayasu arteritis is unknown. The disease occurs mainly in children and women younger than 30, especially those who are of Asian or African descent. It appears to be an autoimmune condition, where immune cells are wrongly targeted against the body's own tissues, and it may involve other systems. Symptoms
Exams and Tests
There may also be signs of inflammation (pericarditis or pleuritis). Tests:
TreatmentTreatment of Takayasu arteritis is difficult, but patients who do have the right treatment can see positive results. Early detection is important. Most patients are treated with steroids and immunosuppressive drugs. Surgery is reserved for complications caused by narrowed arteries. Surgery to bypass narrowed arteries -- angioplasty or stent placement -- may be needed to supply blood or open up the constriction. Outlook (Prognosis)This disease can be fatal. However, with a combination of aggressive medical and surgical treatment, death rates have dropped dramatically. In well-managed cases of Takayasu arteritis, the long-term survival rate is greater than 90%. The survival rate is better for adults than for children. Possible Complications
When to Contact a Medical ProfessionalCall your health care provider if you have symptoms of this condition. Weak pulse, chest pain, and breathing difficulty require immediate care. ReferencesMaksimowicz-McKinnon K, Hoffman GS. Takayasu arteritis: what is the long-term prognosis? Rheum Dis Clin North Am. 2007;33:777-786.Review Date: 1/17/2008
Reviewed By: Neil J. Gonter, MD, Assistant Professor of Medicine, Columbia University, NY and private practice specializing in Rheumatology at Rheumatology Associates of North Jersey, Teaneck, NJ. Review provided by VeriMed Healthcare Network. The information provided herein should not be used during any
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