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  • COBRE Center for Cancer Research and Development at Rhode Island Hospital

  • Kate Brilliant

  • Kate BrilliantKate Brilliant
    Research Facilitator

    Kate Brilliant, MS, is the research facilitator for the COBRE CCRD. Prior to joining the CCRD she was employed as a senior research assistant in the laboratory of Douglas Hixson, MD. Brilliant is a highly skilled technician with extensive experience in areas of rodent surgery, cell isolations, transplantation techniques, various carcinogenesis protocols and manuscript preparation.

    A native of Massachusetts, she holds bachelor and masters of science degrees in biology. As part of Brilliant's responsibilities as the CCRD research facilitator she will assist investigators, establish collaborations, procure essential reagents, antibodies, PCR primers, vectors, tissue/antibody/gene arrays and cell lines. For studies involving animal protocols, she will obtain or assist with ALAAC approval, arrange for purchasing or breeding of required animals, assist with surgeries, treatments, transplants or tissue harvests and help orchestrate various in vivo and in vitro analytical aspects of the experiments.


    Aliotta, J.M., Pereira, M., Johnson, K.W., de Paz, N., Dooner, M.S., Puente, N., Ayala, C., Brilliant, K., Berz, D., Lee, D., Ramratnam, B., McMillan, P.N., Hixson, D.C., Josic, D., & Quesenberry, P.J. (2010). Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription. Exp Hematol, 38 (3), 233-245.

    Mills, D.R., Haskell, M.D., Callanan, H.M., Flanagan, D.L., Brilliant, K.E., Yang, D., & Hixson, D.C. (2010). Monoclonal antibody to novel cell surface epitope on Hsc70 promotes morphogenesis of bile ducts in newborn rat liver. Cell Stress Chaperones, 15 (1), 39-53.

    Clifton, J., Huang, F., Gaso-Sokac, D., Brilliant, K., Hixson, D., & Josic, D. (2010). Use of proteomics for validation of the isolation process of clotting factor IX from human plasma. J Proteomics, 73 (3), 678-688.

    Brilliant, K.E., Mills, D.R., Callanan, H.M., & Hixson, D.C. (2009). Engraftment of syngeneic and allogeneic endothelial cells, hepatocytes and cholangiocytes into partially hepatectomized rats previously treated with mitomycin C. Transplantation, 88 (4), 486-495.

    Simper-Ronan, R., Brilliant, K., Flanagan, D., Carreiro, M., Callanan, H., Sabo, E., & Hixson, D.C. (2006). Cholangiocyte marker-positive and -negative fetal liver cells differ significantly in their ability to regenerate the livers of adult rats exposed to retrorsine. Development, 133 (21), 4269-4279.

    Laurie, N.A., Comegys, M.M., Carreiro, M.P., Brown, J.F., Flanagan, D.L., Brilliant, K.E., & Hixson, D.C. (2005). Carcinoembryonic antigen-related cell adhesion molecule 1a-4L suppression of rat hepatocellular carcinomas. Cancer Res, 65 (23), 11010-11017.

    Comegys, M.M., Lin, S.H., Rand, D., Britt, D., Flanagan, D., Callanan, H., Brilliant, K., & Hixson, D.C. (2004). Two variable regions in carcinoembryonic antigen-related cell adhesion molecule1 N-terminal domains located in or next to monoclonal antibody and adhesion epitopes show evidence of recombination in rat but not in human. J Biol Chem, 279 (33), 35063-35078.

    Leahy, M., Roderick, R., & Brilliant, K. (2001). The cranberry - promising health benefits, old and new. Nutrition Today, 36 (5), 254-265.