Rena Wing, PhD
Director, Weight Control and Diabetes Research Center
196 Richmond Street
Providence, RI 02903
Prevention of Postpartum Weight Retention
The primary goal of this project is to test the effects of a behavioral lifestyle intervention in promoting healthy weight gain during pregnancy and preventing postpartum weight retention.
Principal Investigator: Rena R. Wing, PhD
Funding Agency: National Institute of Diabetes and Digestive and Kidney Diseases
Dates: 2006 - 2010
The Look AHEAD Continuation: Action for Health in Diabetes
Look AHEAD is a randomized clinical trial examining the long-term health effects of an intensive weight loss intervention in approximately 5,145 overweight volunteers with type 2 diabetes. Participants are randomized to an intensive lifestyle intervention designed to achieve and maintain weight loss by decreased caloric intake and increased physical activity, or to a control program of diabetes support and education. The primary outcome of Look AHEAD is the aggregate occurrence of severe cardiovascular events (fatal and non-fatal Ml and stroke and cardiovascular deaths) over a planned follow-up of 11.5 years. The continuation of this project allows for completion of follow up outcome assessments and the continued administration of the lifestyle intervention. These procedures will enable us to analyze the effects of the intervention on serious cardiovascular- related factors and complications, and cost-effectiveness of the intervention. (5U01DK056992-11)
Co-Investigators: Vincent Pera, MD; Jeanne McCaffery, PhD
Funding Agency: National Institute of Diabetes and Digestive and Kidney Diseases and the National Institute of Nursing Research
Dates: 1999 - 2013
Gene X Behavioral Interaction in the Look AHEAD Study
The primary goal of this grant is to identify genetic markers that interact with behavioral weight loss treatment to predict the extent of weight loss.
Principal Investigator: Rena R. Wing, PhD; Jeanne McCaffery, PhD
Dates: 2009 - 2013
Prevention of Weight Gain in Young Adults
"STOP (Study toPrevent) Weight Gain" is a randomized clinical trial testing two innovative interventions to prevent weight gain over an average 3 years of follow-up in individuals 18 to 35 years of age. This study will compare these interventions to each other and to a control condition in a 3-armed randomized controlled clinical trial.
Co-Investigators: Jessica LaRose, PhD; Jeanne McCaffery, PhD
Funding Agency: National Heart, Lung, and Blood Institute
Dates: 2009 - 2014
Lifestyle Intervention to Treat Erectile Dysfunction (LITE)
The purpose of this planning grant is to plan a randomized clinical trial to test the efficacy of lifestyle intervention in obese men with erectile dysfunction.
Co-Investigator: Dale Bond, PhD
Dates: 2009 - 2011
Innovative Technology to Improve Patient Adherence to Weight Loss Recommendations
The purpose of this project is to use innovative technology to improve adherence to behavioral weight loss strategies.
Co-Investigators: Graham Thomas, PhD
Increasing Sleep Duration: A Novel Approach to Weight
This project, which establishes the Center for Behavioral Intervention Development (CBID), seeks to translate the basic science on sleep duration into a novel intervention to reduce obesity and obesity-related co- morbidities. The project involves a programmatic series of studies to develop a sleep and weight loss intervention. The target population for these studies will be young adults (age 25 - 45) where the association between sleep duration and obesity appears strongest, who are overweight or obese (BMI 25 - 40), and who currently sleep less than six and a half hours per night. This series of studies will be used to examine the effects of increases in sleep duration alone and in combination with a weight loss program on eating and exercise behaviors (measured objectively), and ultimately on body weight. The effects of increasing sleep duration on physiological, psychological and cognitive changes that may relate to the changes in eating and activity and adherence to weight control recommendations will also be examined. The CBID creates a new interdisciplinary team, including investigators in the areas of behavioral weight control, basic and clinical aspects of sleep, fMRI and neuropsychological assessment of cognitive function, eating and exercise behavior, and physiological changes associated with sleep and weight. (U01 CA150387-01)
Co-Investigators: Dale Bond, PhD; Mary Carskadon, PhD; Robert Considine, PhD; Ron Cohen, PhD; Joseph Fava, PhD; Chantelle Hart, PhD; Jeanne McCaffery, PhD; Richard Millman, MD; George Papandonatos, PhD; Donn Posner, PhD; Hollie Raynor, PhD; Katherine Sharkey, MD; and Larry Sweet, PhD
Funding Agency: National Cancer Institute