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  • Cardiovascular Research

    Frank Selke, MD, chief of the division of cardiothoracic surgery, discusses ongoing cardiac research at Rhode Island and The Miriam Hospitals.

    At the Cardiovascular Institute, our mission is to continually advance our knowledge through the development of new diagnostic methods and treatments. Our researchers are at the forefront of cutting-edge cardiac research, much of it translational research, which brings new discoveries and treatments directly from the lab to the patient. Our eligible patients are frequently offered the opportunity to participate in clinical research, giving them access to the newest treatments.

    As leading teaching hospitals of The Warren Alpert Medical School of Brown University, Rhode Island and The Miriam hospitals have active cardiology fellowship training programs and serve as on-site training facilities for medical students, residents and fellows.

    Centers for Behavioral and Preventive Medicine: The Centers for Behavioral and Preventive Medicine at The Miriam Hospital have received significant support, totaling millions of dollars, from the National Institutes of Health to study cardiac patients participating in the cardiac rehabilitation and maintenance programs. The research explores the link between depression and heart disease, evaluates the benefits of cardiac rehabilitation for men and women, and tests interventions aimed at helping patients stay physically active following a supervised cardiac rehabilitation program.

    Cardiovascular Research Center: In affiliation with The Warren Alpert Medical School of Brown University, the Cardiovascular Research Center conducts research on topics such as new blood tests for sudden death, stroke risk prediction, and diagnosing types of heart failure. Center researchers are developing new catheter-based approaches to treat heart disease, new therapies for systolic and diastolic heart failure, and new therapies to prevent arrhythmias and sudden death. Through translational research, which brings research breakthroughs from the laboratory to clinical trials as quickly as possible, basic and clinical researchers work together to “translate” new discoveries into promising therapies for patients. Successes include a new biotech startup company, 3PrimeDx, which is developing a blood test to predict the need for an implanted defibrillator.

    Vascular Disease Research Center: The Vascular Disease Research Center is a center of excellence for peripheral vascular disease research that is funded by the National Institutes of Health. The center also coordinates a number of Food and Drug Administration (FDA) studies at Rhode Island Hospital.