Rhode Island Hospital
Online Newsroom
 Brian
Ott, MD
Brian Ott, MD, is the director of the Alzheimer's
Disease and Memory Disorders Center at Rhode Island Hospital
and a professor of medicine in the department of clinical neurosciences
at Brown Medical School, both in Providence, RI. He is a neurologist
specializing in memory disorders and a leader in Alzheimer's disease
research.
The Alzheimer's Disease and Memory Disorders Center at Rhode Island
Hospital is the largest memory assessment program in Rhode Island
and offers a full range of diagnostic and treatment services including
cutting-edge brain imaging, genetic tests and neuropsychological
evaluations. In addition, numerous clinical trials of new and promising
treatments to delay or slow memory loss are offered.
Ott's research has focused on behavioral problems caused by Alzheimer's
disease and mild cognitive impairment; vascular dementia; neuroimaging
in dementia; gender differences and hormonal factors in Alzheimer's
disease. Currently he is leading a study to define the basis of
driving impairment in Alzheimer's disease and to develop computerized
test predictors of impaired road test performance and driving ability.
He is on the steering committee of the Alzheimer's Disease Neuroimaging
Initiative—a study to develop improved methods which will lead
to uniform standards for acquiring regular MRI and PET data on persons
with Alzheimer's disease, mild cognitive impairment, and normal
elderly in order to help predict and monitor the onset and progression
of Alzheimer's disease. He is on the steering committee and internal
ethics committee of the Alzheimer's Disease Cooperative Study, a
consortium of NIH-funded research centers that conducts multi-center
clinical trial to evaluate the effectiveness of medications on dementia
and delaying the progression of Alzheimer's and its symptoms. Currently
he is involved with a study to determine the efficacy of valproate
in slowing the progression of Alzheimer's disease and reducing the
development of behavioral problems; a study to examine the relationships
between semantic deficits in Alzheimer's disease and attention using
electrophysiological event-related potentials; a functional MRI
study to investigate the utility of sensory integration as a marker
for early detection and progression of AD.
Ott lectures extensively on Alzheimer's disease and is a reviewer
for several journals, including Neurology, Journal of
the American Geriatrics Society, Journal of Geriatric Psychiatry
and Neurology, Neuropsychopharmacology and the International
Journal of Geriatric Psychiatry. He is on the editorial board,
Neurological Disease section, for Health and Quality of Life Outcomes.
He is an author or co-author of more than 100 publications and abstracts.
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