Mood Disorders Program
Ongoing/Upcoming Studies
 The
Mood Disorders Program at Rhode Island Hospital evaluates and treats
mood disorders such as major depression, chronic major depression
and bipolar disorder. This program is affiliated with Brown University
and conducts studies sponsored by the National Institute of Mental
Health, private foundations, pharmaceutical companies, and the Department
of Psychiatry at Brown University.
Ongoing/Upcoming Studies
- Bipolar Depression
This study will compare the use of aripiprazole to placebo in
the treatment of patients suffering from a depressive episode
of Bipolar I disorder. This study will be conducted over 35 sites
nationwide and enroll approximately 420 patients. We expect to
enroll 12 patients at Rhode Island Hospital.
- Bipolar Mania
This double-blind placebo-controlled trial is designed to
study the effectiveness of licarbazepine (an anticonvulsant like
depakote or tegretol) when combined with risperidone in the treatment
of patients experiencing a manic or mixed episode of Bipolar I
disorder. There is also a possible extension study that lasts
52 weeks for patients who have successfully completed the core
trial.
- Managing Depression
This study will offer an intervention for depressed patients
who continue to experience depressive symptoms in spite of their
treatment. It is designed to assist patients and their families
to manage their depression. Patients will receive both family
and individual sessions over a 16-week period. We hope to enroll
15 patients for this study.
- A Pilot Trial of Psychotherapy for Patients
with Nonepileptic Seizures
This is an open clinical trial for patients diagnosed with nonepileptic
seizures (NES) by video EEG. It is designed to evaluate the effectiveness
of family therapy or cognitive behavioral therapy in the treatment
of patients with NES.
- Family Functioning and Quality of Life
in Patients with Epilepsy
Patients and their families are currently participating in this
year-long study that looks at the relationships between family
functioning, quality of life, and symptoms of epilepsy. The information
that we collect from this study will help us better understand
how symptoms of epilepsy affect family life. This information
will help us to provide better treatment for patients and their
families.
- Treatment for Nonepileptic Seizures
This ongoing study is a placebo-controlled trial of sertraline
for patients who experience nonepileptic seizures (NES); this
study is one part of a program to develop combined treatments
of psychosocial treatments and medication for these patients with
NES.
Qualified research participants receive:
- A comprehensive psychiatric evaluation to establish diagnosis
and to evaluate severity.
- Careful monitoring of disorder by a professional team of clinicians
and researchers.
- Treatment protocols may include medication and/or individual
and family therapies.
- A multi-disciplinary team approach to treatment by psychiatrists,
psychologists, and family therapists.
- Free assessments and outpatient appointments
- Reimbursement for participation in certain research studies
Research programs are at no cost to eligible participants.
For more information or to find out whether you qualify
for one of the ongoing studies in the Mood Disorders Program at
Rhode Island Hospital, please call 401-444-3937.
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