Coronavirus (COVID-19)

COVID-19 Monoclonal Antibody Infusion Centers

The US FDA recently granted emergency use authorization (EUA) to two monoclonal antibody infusions for treatment of mild-to-moderate COVID-19 in the outpatient setting: bamlanivimab and casirivimab/imdevimab. Studies have shown that these antibody infusions may reduce the need for hospitalization in high-risk patients. The State of Rhode Island has received a limited supply of these medications for use, and the available inventory has been divided among hospital systems across the state. 

Both monoclonal antibody infusions are delivered in the outpatient setting as a one-hour infusion. Patients should be referred by their primary care provider or urgent care provider to the Infectious Diseases (ID) Center using the referral form below. Eligible patients must be symptomatic, fairly early on in symptoms, and at high risk for hospitalization. Eligible patients will be evaluated by the ID clinical team for eligibility and a risk assessment. Due to the extremely limited number of doses received, the infusion will be offered to highest risk patients, and then by lottery for remaining available appointments. 

If you meet the criteria below and are interested in this treatment, please speak with your primary care or urgent care provider about a referral.

Information for Referring Providers

Hours of Service

Referral hours of operation are Monday through Friday, 8 a.m. to 4:30 p.m.

Eligibility Criteria

Patients must meet the criteria as defined in the EUA:

  1. Patient with confirmed COVID-19
  2. Patient is symptomatic and presenting within 10 days of symptom onset and hospital admission is NOT anticipated
  3. Patient is NOT requiring supplemental oxygen due to COVID-19 (or, if on home O2, no changes from baseline requirement)
  4. Patient is at high risk for progressing to severe COVID-19 and/or hospitalization. In order to be considered high risk, patients MUST meet one of the following criteria:
    • Age ≥ 65 years 
    • Age ≥ 55 years AND have at least one of the following conditions:
      • Cardiovascular disease
      • Hypertension
      • Chronic obstructive pulmonary disease/other chronic respiratory disease 
      • Body mass index (BMI) ≥ 35 
      • Chronic kidney disease 
      • Diabetes 
      • Immunosuppressive disease or receiving immunosuppressive therapies 
    • Age 18-54 years AND have at least one of the following conditions:
      • BMI ≥ 35 
      • Chronic kidney disease 
      • Diabetes 
      • Immunosuppressive disease or receiving immunosuppressive therapies

Information to Review with Eligible Patients

If a patient is eligible and you would like to refer them, please review both EUA fact sheets below with the patient and ensure the patient agrees to treatment. Final determination of which monoclonal antibody the patient receives will be determined by available inventory or will be at the discretion of the ID physician.

How to Refer a Patient

Please review the referring provider checklist below, then fill out referral form and fax to Lifespan at 401-793-4351.

More Information

Please call the Lifespan Infectious Diseases Center at 401-793-2928 with any questions.