How to Find Us

The Core Research Laboratories are located: 
Coro West Building 
1 Hoppin St, 4th floor, rooms 4.211 and 4.213, Providence, RI 02902.

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Who We Are and What We Do

Core Research Laboratories is a network of centralized facilities located at Rhode Island Hospital, Providence, Rhode Island. We offer a broad spectrum of technical services to the research community on a fee-for-service basis. 

Core Research Labs Price List »

Digital Imaging and Analysis

 

The digital imaging and analysis lab at Rhode Island Hospital offers full service confocal acquisitions, image processing, digital imaging and quantitative image analysis.  Microscopes and high-resolution camera are available for self-service imaging after training.

Available Equipment and Software

The Nikon C1si spectral (full-service confocal) features:

  • Four diode lasers: 402, 488, 561, 638 
  • Spectral capabilities for multiple stained specimens ranging from 400 nm to 700 nm
  • Environmental chamber for live cell imaging
  • Timed events
  • Time-lapse movies
  • Colocalization analysis
  • Volume measurments
  • Deconvolution software
  • 3D software
  • Post-acquisition analysis and image processing for publication quality images

Other available microscopes and software (full- or self-service) include:

  • Nikon TE200, inverted; brightfield, phase, fluorescence and DIC modes
  • Nikon E800, upright; brightfield, fluorescence, DIC
  • Spot RT3 high-resolution camera
  • National Insitute of Health (NIH) ImageJ
  • Adobe Photoshop

For more information, contact Ginny Hovanesian by phone at 401-444-4793, or email at vhovanesian@lifespan.org

Electron Microscopy

Electron microscope-related services are now being offered through University of Massachusetts Medical center www.umassmed.edu/cemf/

For more information contact Gregory Hendricks, MD, at 508-856-2602 or email at Gregory.Hendricks@umassmed.edu.

Histology

 

The histology laboratory provides histological and cytological services:

  • Processing
  • Embedding
  • Sectioning: frozen, paraffin, methacrylate, et. al.
  • Staining: conventional, immunological, et.al.
  • Cytological procedures: cytospins, cell pellets, cell cultures, smears, et. al

The following techniques are available:

  • Cytochemistry/histochemistry
  • Immunohistochemistry
    • Immunofluorescence
    • Immunoperoxidase
  • Lectin histochemistry
  • Enzyme histochemistry

Techniques can be customized to meet specific requirements.

For more information, contact Loli Noble at 401-444-3815 or 401-444-3816; email: lnoble@lifespan.org.