Pediatric Endocrinology and Diabetes Center
Hasbro Children’s Hospital is the pediatric division of Rhode Island Hospital, the principal teaching hospital of The Warren Alpert Medical School of Brown University. Our physicians are faculty members of the school, where they train the next generation of physicians and engage in research to develop new and more effective treatments for endocrine diseases.
Current research projects include:
- The TrialNet Natural History Study of the Development of Type 1 Diabetes:
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- Urinary Biomarker Study to Predict Kidney Disease in Children with Type I, Type 2 Diabetes and Obesity in children.
- American Norditropin Studies: Registry of Growth Hormone (GH) Patients (ANSWERProg)
The division’s laboratories are home to a basic research program that focuses on the regulation of normal and abnormal cell growth. In recent years, areas of research have included control of cell division and protein synthesis during liver development; the effects of nutrient signaling on growth plate chondrogenesis; hormonal control of adipogenesis; and fetal metabolic programming through epigenetic mechanisms. In addition to standard cell biology techniques, the lab routinely employs high-throughput genomic and proteomic analyses.