Infectious Diseases

Infectious Diseases Clinical Research

The Miriam Hospital clinical trials unit offers the newest treatments for HIV and hepatitis C (HCV) infections. The experienced research staff consists of physicians, nurses, a data manager, a regulatory assistant and laboratory personnel.

We conduct trials offered through the AIDS Clinical Trials Group (ACTG) network, funded by the National Institutes of Health, in association with the Partners/Harvard AIDS Clinical Trials Unit. The priority of ACTG studies is to evaluate new strategies for treating HIV infection and preventing HIV complications, and to evaluate new treatments for hepatitis C.

Other studies offered through our clinical trials unit include pharmaceutical studies to treat hepatitis C, prevent C. difficile infection, and test new methods of diagnosing HIV infection.

Currently Enrolling Research Studies

COVID-19 Studies


Funded by the National Institutes of Health (NIH), the PreventCOVIDU research study is being conducted across the United States to learn about the Moderna COVID-19 vaccine impact on the spread of COVID-19. Eligible participants will be compensated for their time.

Key Requirements:

  • Adults under the age of 30
  • Must not be vaccinated
  • A vaccine will not be offered to participants
  • Have never had a known COVID-19 infection
  • Must be willing to self-swab daily, for four months

For more information, email The Miriam Hospital at, call 401-793-4317, or visit

ACTIV-2/A5401 – Adaptive Platform Treatment Trial for Outpatients with COVID-19 (Adapt Out COVID)

Evaluate the safety and efficacy of investigational agents, both infused and non-infused, for the treatment of symptomatic non-hospitalized adults with COVID-19.

Key Requirements

  • Ages 18 and above
  • Positive COVID-19 test within the past 10 days
  • Onset of symptoms within 8 days
  • Must have at least one currently occurring symptom

For more information, please visit: or call 877-345-8813

HIV Studies

Alcohol-HIV Study

Study the effects of alcohol on the immune system and the brain.

Key Requirements

  • Ages 21-60
  • Able to consume alcohol safely
  • Able to consume nuts and soy safely
  • Able to attend 2 visits at the Brown School of Public Health
  • Free of metal devices or implants in the body
PNAV Smoking Cessation Study

Examine whether using a peer navigator to help smokers with smoking cessation will increase quit attempts among HIV-positive individuals.

Key Requirements

  • Must be HIV-positive
  • Must be currently smoking