Specialized Equipment and Services

The BOND RXm is an automated staining system that increases reproducibility of IHC (chromogenic or immunofluorescent) and multiplex staining.

Researchers can design their ideal protocol with customization options across all protocol editing segments. The system is fully automated and provides unmatched protocol. Flexibility and fully open reagents, allowing researchers to retain complete control of their staining.

Features of the BOND RX include:

• Users could directly edit the temperature of any step (reagent or wash step) in ISH and IHC staining protocols, single or sequential double staining protocols and parallel double staining protocols
• Eliminate manual or semi-automated staining
• Protocol flexibility and choice of reagents
• Fully automated IHC, ISH and emerging tests
• Reduce process variability with full automation
• Protect tissue with the unique Covertile system

The Autostainer Link 48 ensures optimal staining results and offers a high slide and reagent capacity. It delivers high-quality staining, maximum versatility, and high productivity.

Features of the Autostainer Link 48 include:

• Instrument precision and stability
• Optimized reagents and protocols
• Flexible run options
• Process 48 slides in less than three hours
• Process slides in parallel using PT Link

The Aperio VERSA is a comprehensive digital pathology scanner, designed and developed to support the diverse imaging needs of cutting-edge research facilities. The combination scanner is optimized for precision scanning of brightfield and fluorescent samples, with the accuracy and resolution required for FISH.

From tissue-based and proteomic markers, to subcellular, molecular, and in-situ hybridization probes, the Aperio VERSA delivers high-resolution, reliable imaging. 

The Aperio VERSA is ideal for scanning multiplex slides at any magnification from 5x to 40x for the whole slide without the need for spectral imaging. It delivers excellence in IHC, ISH and Fluorescent Tissue-Based Research including multiplex whole slide scanning.

Features of the Aperio VERSA include:

• Advanced tissue detection for faint for lightly stained brightfield and fluorescent samples
• Scan slides from 0.9mm to 1.2mm thick
• Z-stack capture for thick samples
• 2-D scanning technology, ideal for co-localization studies
• Broad range of compatible image analysis solutions
• Scan 15mmx15mm @20x brightfield in 206 seconds

The Aperio VERSA has the following filters:

1. Blue: emission filters: 460/50m, excitation filters: 360/50x
2. Green: emission filters: 537/29m, excitation filters: 495/25x
3. Orange: emission filters:572/23m, excitation filters: 546/10x
4. Red: emission filters of 625/30m, excitation filters: 580/25x

Our laboratory is at the forefront of digital pathology, transforming the way we extract pivotal information from images using advanced digital image processing techniques. We specialize in computerized morphometry of microscopic images obtained from both experimental animals and human tissues or cells. Our work extends to the quantification of various biological markers in immunohistochemically stained tumor cells, including biopsies and tissue microarrays.

What sets our lab apart is our commitment to innovation and precision. We have transitioned from using standard software to pioneering our own in-house developed algorithms. These bespoke algorithms, in conjunction with Qupath, offer unparalleled accuracy and efficiency in image analysis. Our state-of-the-art imaging systems are equipped with these custom solutions, providing investigators with the most advanced tools for their research endeavors.

Through this blend of technological mastery and scientific insight, we're not just observing the microscopic world; we're unlocking its secrets to advance our understanding of complex biological systems.

The Hitachi HT7800 Bio-TEM 120 kV transmission electron microscope and is designed for superior biological imaging.

The HT7800 has many convenient features to aid in image acquisition, including:

• A dual-mode objective lens that supports easy observation under low magnification, wide-field high contrast and high resolution.
• Advanced stage-navigation function that enables whole-grid searching and efficient image acquisition. Motorized Z stage.
• Automated image stitching, 3D tomography, automated multi-frame panoramic function, drift correction, auto pre-irradiation, pneumatic objective apertures and electron beam tomography.
• Single and three specimen holders.
• AMT NanoSprint43 MkII 43mp CMOS camera.